Mots-C

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)

History

MOTS-c is a naturally occurring peptide encoded within mitochondrial DNA. It was discovered in 2015 and has attracted significant research interest for its potential role in regulating metabolism, cellular energy production, and healthy aging.

Research Use

Researchers study MOTS-c for its potential effects on:

• Metabolic health

• Energy production

• Exercise performance

• Insulin sensitivity

• Healthy aging

• Cellular stress response

Clinical Highlights

• Studied for improving insulin sensitivity and glucose metabolism

• Investigated for supporting mitochondrial function and cellular energy production

• May enhance exercise capacity and physical performance in research settings

• Explored for promoting metabolic resilience during aging

• Research continues to evaluate its role in age-related and metabolic disorders